Publications

22. Peng, Y., Tai, Y., Zhang, K., & Cheng, X. (2017). Imaging the onset kinetics of the swarming transition using light-controlled bacteria. Bulletin of the American Physical Society, 62.

21. McClintock, Maria, Jilong Wang, and Kechun Zhang. "Application of Nonphosphorylative Metabolism as an Alternative for Utilization of Lignocellulosic Biomass." Frontiers in Microbiology 8 (2017): 2310.

20. Abdelrahman, Omar A., Dae Sung Park, Katherine P. Vinter, Charles S. Spanjers, Limin Ren, Hong Je Cho, Kechun Zhang, Wei Fan, Michael Tsapatsis, and Paul J. Dauenhauer. "Renewable Isoprene by Sequential Hydrogenation of Itaconic Acid and Dehydra-Decyclization of 3-Methyl-Tetrahydrofuran." ACS Catalysis 7, no. 2 (2017): 1428-1431.

19. Bai, W., Tai, Y. S., Wang, J., Wang, J., Jambunathan, P., Fox, K. J., & Zhang, K. (2016). Engineering nonphosphorylative metabolism to synthesize mesaconate from lignocellulosic sugars in Escherichia coli. Metabolic engineering, 38, 285-292.

18. Zhang, C., Schneiderman, D. K., Cai, T., Tai, Y. S., Fox, K., & Zhang, K. (2016). Optically Active β-Methyl-δ-Valerolactone: Biosynthesis and Polymerization. ACS Sustainable Chemistry & Engineering, 4(8), 4396-4402.  

17. Jambunathan, P., and Zhang, K.Engineered biosynthesis of biodegradable polymers.J. Ind. Microbiol. Biotechnol. 2016 Aug;43(8):1037-58.

16. Wang, J., Niyompanich, S., Tai, Y. S., Wang, J., Bai, W., Mahida , P., ... & Zhang, K. (2016). Engineering of a highly efficient Escherichia coli strain for mevalonate fermentation through chromosomal integration. Applied and environmental microbiology, 82(24), 7176-7184.

15. Peng, Y., Lai, L, Tai, Y.S., Zhang, K., Xu, X., and Cheng, X.Diffusion of an ellipsoid in bacterial suspensions.Phys. Rev. Lett.2016 Feb 12;116(6):068303.

14. Tai, Y.S., Xiong, M., Jambunathan, P., Wang, J., Wang, J., Stapleton C. and Zhang, K.Engineering Nonphosphorylative Metabolism to Generate Lignocellulose-derived Products. Nat. Chem. Biol.2016 Apr;12(4):247-53.

13. Xiong M., Yu P., Wang J., Zhang, K. Improving Engineered Escherichia coli strains for High-level Biosynthesis of IsobutyrateAIMS Bioengineering2015, 2(2): 60-74.

12. Tai, Y.S., Zhang, K. 2015. Enzyme Assisted Plant oil-based polymers. In: Kessler, M.R., Zhang, C., and Madbouly, S. (eds.) Plant oil-based polymers and composites. Oxford: Elsevier.

11. Tai, Y.S., Zhang, K. 2015. Enzyme pathways: C1 metabolism redesignedNature Chemical Biology 2015, 11:384–386.

10. Wang, J., Zhang, K. Production of Mesaconate in Escherichia coli by Engineered Glutamate Mutase Pathway. Metab. Eng. 2015 Jul;30:190-6. doi: 10.1016/j.ymben.2015.06.001. 

9. Jambunathan, P., and Zhang, K. Combining biological and chemical approaches for green synthesis of chemicalsCurr. Opin. Chem. Eng. 2015, 10, 35–41.

8. Tai, Y.S., and Zhang, K. Designing bacteria to produce esters Springer Protocols Hydrocarbon and Lipid Microbiology Protocols. 

7. Tai Y.S., Xiong M., Zhang K. Engineered biosynthesis of medium-chain esters in Escherichia coliMetab. Eng. 2015 Jan;27:20-8. doi: 10.1016/j.ymben.2014.10.004. 

 

6. Xiong, M.;* Schneiderman, D. K.;* Bates, F. S.; Hillmyer, M. A.;#Zhang, K.#Scalable production of mechanically tunable block polymers from sugar.Proc. Natl. Acad. Sci. USAFeatured inChemical & Engineering News.   

 

5. Jambunathan, P., and Zhang, K.Novel pathways and products from 2-keto acids. Curr. Opin. Biotechnol. 2014 29C:1-7.

4. Dhande, Y.K., Xiong M., Zhang, K.Production of C5 carboxylic acids in engineered Escherichia coliProcess Biochem. 2012, 47:1965–1971.

3. Xiong M., Deng J., Woodruff A.P., Zhu M., Fu Y., Zhang, K. A Bio-Catalytic Approach to Aliphatic Ketones. Sci. Rep., 2012, 2:311.

2. Zhang, K., Woodruff A.P., Xiong M., Zhou, J. and Dhande, Y.K.A Synthetic Metabolic Pathway for Production of Platform Chemical Isobutyric Acid. ChemSusChem 2011. Jul 8. doi: 10.1002/cssc.201100045.

 1. Yu, P., Tai Y.S., Xiong M., Zhang, K.Engineering artificial metabolic pathways for biosynthesis. Curr. Opin. Chem. Eng. 2012, 1(4):373-379.

 

Patents

1) Zhang, K. and Xiong, M. Biosynthetic pathways and products (β-methyl-δ-valerolactone). US2014/034588, 2014

2) Hillmyer M., Schneiderman D., Bates F., and Zhang K. Poly(beta-methyl-delta-valerolactone) block polymers, US2015/026325, 2015. 

3) Zhang, K., and Xiong, M. Biosynthetic pathways and methods (for TCA derivatives such as 1,4-butanediol).US2013/076118, WO2014100173.  Application date Dec 18, 2012

4) Zhang, K., and Xiong, M. Biobased synthesis of a novel polymer monomer. US2014/034588.

5) Zhang, K., Xiong, M. and Tai, Y.S. . Biosynthetic pathways, recombinant cells, and methods (for producing esters). WO2013180810 A1, PCT/US2013/031470, Application date May 29, 2012.

6) Zhang, K., Xiong, M. and Woodruff, A.P. Cells and methods for producing isobutyric acid. WO 2012/109534, PCT/US2012/024640, Application date Feb 11, 2011.

7) Zhang, K., and Dhande, Y.K. Biosynthetic pathways, recombinant cells, and methods (for producing C5 acids). WO2013169350. PCT/US2013/030719.Application date May 11, 2012.      

8) Zhang, K., Biocatalysis cells and methods (for producing isovalerate and isocaproate). WO2013055667. PCT/US2012/059321. Application date Oct 10, 2011.

9) Dauenhauer, P, Spanjers,C., and Zhang, K. "Methods of forming diol compounds." U.S. Patent Application No. 15/491,236.

Before UMN

1. Marcheschi R.J.,* Li H., * Zhang K.,* Noey E., Kim S., Li H.,  Chaubey A., Houk K.N,  Liao J.C. (2012) “A Synthetic Iterative “+1” Pathway for Carbon Chain Elongation”,ACS Chem. Biol.In press. (*equal contribution)

2. Zhang K, Li H, Cho K, Liao JC. Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine. Proc. Natl. Acad. Sci. USA 2010 107, 6234-6239.

3. Zhang K, Sawaya MR, Eisenberg DS, Liao JC. Expanding metabolism for biosynthesis of nonnatural alcohols.Proc. Natl. Acad. Sci. USA. 2008 105, 20653-20658. (highlighted by PNAS commentary, CBS2,  Popular Mechanics, Nature Chemical Biology,Discover Magazine, New Scientist and MIT TechReview, etc.)

4.  Zhang K, Diehl MR, Tirrell DA. Artificial polypeptide scaffold for protein immobilization. J. Am. Chem. Soc. 2005 127, 10136-10137.

5. Shen W*, Zhang K*, Kornfield JA, Tirrell DA. Tuning the erosion rate of artificial protein hydrogels through control of network topology. Nat. Mater. 2006 5, 153-158.  (* equal contribution)  

6. Diehl MR, Zhang K, Lee H, Tirrell DA. Engineering cooperativity in biomotor-protein assemblies. Science, 2006 311, 1468-1471.

7. Zhang K, Sugawara A, Tirrell DA. Generation of Surface-bound Multicomponent Protein Gradients. ChembioChem, 2009 10, 2617-269

8. Zhang K, Liu L, Mu TW, Guo QX. Ab initio calculations on the inclusion complexation of cyclobis(paraquat-p-phenylene). Chem. Phys. Lett. 2001 333, 195-198.

9. Chen R, Zhang K, Liu L, Guo QX. A quantum chemistry study on the structure and properties of a novel stablestrained cyclophane. Res. Chem. Inter. 2001 27, 911-916.

10. Cheng R, Zhang K, Liu L, Li XS, Guo QX. Substituent effects in X-C  C-H …NH3 (or OH2, FH) hydrogen bonding. Chem. Phys. Lett. 2001 338, 61-66.

11. Zhang K, Fu Y, Lin BL, Liu L, Cheng YH, Guo QX. Nonpolar pi electron delocalization effect on the stabilities of C=C, C=N, andN=N double bonds. J. Mol. Struct. (Theochem) 2003